Generally, standard of care for HRS involves administration of albumin and vasoconstrictors. Terlipressin and norepinephrine are recommended in patients with cirrhosis and HRS-acute kidney injury (AKI; previously termed HRS-1) without high grade of acute-on-chronic liver failure (ACLF) or major cardiopulmonary or vascular disease. The American Association for the Study of Liver Disease states that terlipressin is the preferred vasoconstrictor for HRS-AKI.
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